The Cristo Lemonade Company seemed like a business involved in the making and distribution of lemonade. In reality, it was a front for the delivery of bootleg alcohol in the Chicago area during Prohibition, and was controlled by Dion O'Banion and his gang. They delivered alcohol to speakeasies such as the one owned by Jim Colosimo.
In investigating the murder of Jim Colosimo in May, 1920, Indiana Jones learned that the company delivered to Colosimo's speakeasy. Using the name of the company, Eliot Ness called the harbormaster and learned where the company's shipments were being stored: Warehouse 35.